Promethazine prescribing across the NHS.
Promethazine is the old sedating antihistamine doing several jobs at once: allergy occasionally, but mostly sleep, agitation and nausea, 2.8m items a year and rising. Its availability over the counter as a sleep aid gives this line a shadow twin the data never sees.
The NHS in England dispensed 2,839,526 prescription items of Promethazine in the 12 months to May 2026, across primary care and hospitals.
Spending on Promethazine over those 12 months was £5.6m at net ingredient cost, the list price of what was dispensed before any discounts.
Items were up 6.2% on the previous 12 months.
92% of Promethazine volume moved through primary care and 8% through hospital pharmacies.
Promethazine ranks #3 of 16 chemical substances in Antihistamines (BNF 3.4.1), by items dispensed.
Among Integrated Care Boards, NHS Greater Manchester ICB dispensed the highest volume of Promethazine.
Source: NHS Business Services Authority open data (English Prescribing Data and SCMD), OGL v3.0. Items count prescriptions dispensed, not patients treated.
| Month | Items | Spend (NIC) |
|---|---|---|
| May 2026 | 228,934 | £422k |
| April 2026 | 240,099 | £455k |
| March 2026 | 246,076 | £452k |
| February 2026 | 230,539 | £392k |
| January 2026 | 248,763 | £428k |
| December 2025 | 248,386 | £485k |
| November 2025 | 227,879 | £448k |
| October 2025 | 246,348 | £481k |
| September 2025 | 237,052 | £506k |
| August 2025 | 221,818 | £475k |
| July 2025 | 238,475 | £517k |
| June 2025 | 225,157 | £556k |
The same series as the chart, most recent month first. The full monthly history, as CSV, sits behind Apply.
15.9% of its class.
Promethazine ranks #3 of 16 chemical substances in Antihistamines (BNF 3.4.1), by items dispensed in May 2026. The full class league, who's gaining, and the month-by-month share movement sit behind Apply.
Average items by calendar month across the full history, indexed to the annual mean.
Promethazine across all 36 ICBs.
Every Integrated Care Board in England, shaded by how much promethazine its GPs dispense per head of population. Hover an ICB to name it. The ranked figures for all 36 ICBs, and the drill-down to practice level, are in the full report.
Darker shading marks where Promethazine is dispensed most per head of population. Exact figures for every ICB, and the drill-down to practice level, are in the full report.
Zoomed out to the 7 NHS regions.
The same 12 months rolled up to NHS England's seven regions, ranked by intensity.
The teaser view.
Three rows each. The full 36-ICB view, every prescribing organisation, every strength and the hospital picture sit below the fold, behind Apply.
- 1 NHS Greater Manchester ICB 196k
- 2 NHS West and North London ICB 178k
- 3 NHS Kent and Medway ICB 174k
- – + 33 more. Unlock the full 36-ICB table. Unlock →
- 1 NHS Birmingham and Solihull ICB +14.7%
- 2 NHS Nottingham and Nottinghamshire ICB +14.5%
- 3 NHS Coventry and Warwickshire ICB +14.4%
- – + 33 more. Unlock every ICB, ranked. Unlock →
- 1 Promethazine hydrochloride 25mg tablets 71%
- 2 Promethazine hydrochloride 10mg tablets 16%
- 3 Phenergan 25mg tablets 10%
- – + 3 more. Unlock every strength and pack. Unlock →
Split of items across NHSBSA primary care and SCMD hospital dispensing.
Prescribing by deprivation.
Items per 1,000 registered patients by deprivation decile (1 = most deprived), practice deprivation weighted by where each practice's patients live. Read the shape rather than the absolute level: the most and least deprived deciles cover far fewer practices, and age structure drives much of the gradient.
The devolved nations.
| Nation | Items · 12 months | Data to |
|---|---|---|
| England | 2.8m | May 2026 |
| Northern Ireland | 133k | May 2026 |
| Scotland | 194k | April 2026 |
| Wales | 168k | April 2026 |
Each nation publishes its own community prescribing data, with different coding and list rules, so read these per-nation rather than as an exact UK total. Sources: NHSBSA (England), Public Health Scotland.
What open data won't tell you about promethazine.
Between insomnia, allergy and sickness, indication-blindness bites hard here, and anticholinergic-burden concerns in older patients are invisible in item counts.
Asked and answered.
Is promethazine prescribing rising or falling in the NHS?
Rising. England dispensed 2,839,526 items of Promethazine in the 12 months to May 2026, up 6.2% on the previous 12 months. Items count prescriptions dispensed, not patients treated, so the change can reflect dose and duration shifts as well as patient numbers.
How much does the NHS spend on promethazine?
£5.6m at net ingredient cost in the 12 months to May 2026. Net ingredient cost is the list price of the medicine before discounts and rebates; the NHS's final bill, especially for hospital medicines, is usually lower.
Where in England is promethazine prescribed most?
By raw volume, NHS Greater Manchester ICB dispensed the most promethazine in the last 12 months. Raw volume favours the biggest populations; the map on this page shades every ICB by items per head to correct for that.
How up to date is this data?
This page runs to May 2026, the most recent NHSBSA release. Prescribing data publishes roughly six to eight weeks in arrears, and DoseTrend refreshes within 48 hours of each monthly release.
The full breakdown.
Every ICB, every prescribing organisation, every strength, the hospital view, and the monthly briefing PDF. Sample rows shown below with the numbers obscured.
Related pages.
See the full molecule directory, or read about the data and pricing.
Track promethazine like this, every month.
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